res_timing_timerfd.c:167 timerfd_timer_ack: Expected to acknowledge 1 ticks but got 2 instead

I have a problem with a new S50 pbx:

After about 6 to 10 hours incoming and outgoing calls are not working.

Trunk is ISDN.

I enabled the asterisk + ISDN debug.

When I start the asterisk debug, about 3 times per second the message:

res_timing_timerfd.c:167 timerfd_timer_ack: Expected to acknowledge 1 ticks but got 2 instead

also, from time to time:

db.c:565 db_get_common: Unable to find key 'ABCDEFG' in family 'FORCEDEST' is logged.ABCDEFG is the name of the rule which process incoming calls for on of the DIDs.

is printed. That looks not good.

Any idea what I could do? Of course I can upload the whole log and the pbx config backup if needed.

Thank you.